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PERIPHERAL SMEAR/GENERAL BLOOD PICTURE/GBP

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REASON FOR TESTING OF PERIPHERAL SMEAR / GENERAL BLOOD PICTURE


Examination of the peripheral blood smear should be considered, along with review of the results of peripheral blood counts and red blood cell indices, an essential component of the initial evaluation of all patients with hematologic disorders. It is ordered along with Complete blood count or as a standalone test in following cases.

  • Weakness
  • Paleness
  • Fever
  • Jaundice
  • Easy bruising
  • Enlarged spleen

WHAT IS BEING TESTED IN PERIPHERAL SMEAR


Peripheral smear examination provide information regarding the morphological details of the formed elements, which include:

  • Red blood cells ( RBC )
  • White blood cells ( WBC )
  • Platelets
  • Hemoparasite
  • Any other significant morphological details

INTERPRETATION OF PERIPHERAL SMEAR TEST RESULT


Red blood cells ( RBC )

  • Anisocytosis- variation in size
  • Poikilocytosis- variation in shape
  • Microcyte - common in iron deficiency anaemia
  • Macrocyte - seen in vitamin B 12 and folate deficiency
  • Hypochromic- seen in iron deficiency anaemia
  • Schistocytes - thalassemia, haemolytic anaemia

White blood cells ( WBC )

  • Leucocytosis( increase in white blood cells )- fever,
  • Neutrophilia - increase in neutrophils
  • Lymphocytosis - increase in lymphocytes
  • Eosinophilia- increase in eosinophils
  • Abnormal cells - Band form , metamyleocytes, myelocytes, promyelocytes, Blast

Platelets

  • Thrombocytopenia- decrease in platelet count
  • Thrombocytosis - increase in platelet count

PERIPHERAL SMEAR REFERENCE RANGE


Not applicable


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