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IRON AND TRANSFERRIN AND TIBC AND FERRITIN

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REASON FOR TESTING OF IRON AND TRANSFERRIN AND TIBC AND FERRITIN


These test are ordered in patients whose symptoms confers iron deficiency anaemia like:

  • General fatigue.
  • Weakness.
  • Pale skin.
  • Shortness of breath.
  • Dizziness.
  • Tingling or a crawling feeling in the legs.
  • Swelling or soreness in the tongue.

A serum iron and other iron tests may be ordered when iron overload (hemochromatosis) is suspected.


WHAT IS BEING TESTED IN IRON AND TRANSFERRIN AND TIBC AND FERRITIN


Serum iron, total iron-binding capacity (TIBC), and/or transferrin tests are ordered mostly all together and after that transferrin saturations can be calculated which provide information regarding the how much iron is being carried in the blood. Ferritin confers the total iron stores in the patient .


IRON-AND-TRANSFERRIN-AND-TIBC-AND-FERRITIN


INTERPRETATION OF IRON AND TRANSFERRIN AND TIBC AND FERRITIN TEST RESULT


SNo Iron deficiency Anaemia of chronic disease Iron overload
S. Iron decreased decreased increased
S.Transferrin, TIBC increased decreased decreased
Transferrin Saturation decreased decreased increased
S. Ferritin decreased normal increased

IRON AND TRANSFERRIN AND TIBC AND FERRITIN REFERENCE RANGE


  • Iron: 60 to 170 mcg/dL
  • Transferrin saturation: 20 percent to 50 percent
  • TIBC (total iron binding capacity): 240 to 450 mcg/DL
  • Ferritin - 15-200 ng/ml ( males) , 12-150 ng/ml ( females)

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