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DENGUE SEROLOGY (NS1, IgM, IgG)

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REASON FOR TESTING OF DENGUE


It is ordered when patient complains of following symptoms -

  • High grade fever
  • Body ache
  • Joint pain
  • Bruising

Dengue Test is usually ordered on day 1 of fever or can be ordered within week as different antibodies rise at different time.


WHAT IS BEING TESTED IN DENGUE


NS1 - The non-structural protein 1 (NS1) of the dengue viral genome has been shown to be useful as a tool for the diagnosis of acute dengue infections. It rises from day 1 of the infection.

IgM - Its titre increase 7 to 10 days after the infection.

IgG - Its titre increase 14 to 21 days after the infection.


INTERPRETATION OF DENGUE TEST RESULT


IgM IgG Interpretation
Positive Negative Recent primary infection
Positive Positive Recent secondary infection
Negative Positive Recent secondary infection
Negative Negative No recent infection

NS1 antigen test comes positive from day 1 of infection.


DENGUE TEST REFERENCE RANGE


Not Applicable


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